Endometrial polyps affect uterine receptivity

GnRH antagonists may affect endometrial receptivity.

OBJECTIVE HOXA10 is an essential regulator of endometrial receptivity. To determine the effect of GnRH antagonists on endometrial receptivity, we assessed endometrial HOXA10 expression in GnRH antagonist, GnRH agonist, and natural cycles. DESIGN Prospective case-control study. SETTING University academic medical center. PATIENT(S) Nineteen subjects were included: 12 subjects underwent con...

Hydrosalpinges adversely affect markers of endometrial receptivity.

While in-vitro fertilization (IVF) was initially developed in women with tubal factor infertility, recent clinical studies have suggested that the presence of hydrosalpinges lowers implantation and pregnancy rates. We postulated that these hydrosalpinges cause impaired endometrial receptivity. A total of 103 women with hydrosalpinges were prospectively evaluated, and compared with 55 infertile ...

Endometrial markers of uterine receptivity utilizing the donor oocyte model.

BACKGROUND Ethical constraints limit the ability to study peri-implantation phase human endometrium. In this study, the donor oocyte model was used to study candidate endometrial markers of uterine receptivity. METHODS Archived, paraffin-embedded tissue obtained by endometrial biopsy during cycle days 21-23 of patients undergoing 'mock' hormonal treatment cycles were evaluated by standard his...

I-28: Uterine Receptivity

Redefining Endometrial Receptivity

However, the notion of receptivity as a static state in which the tissue is poised, frozen in time, awaiting the arrival of an adequately developed embryo, is naïve. An integrative definition of receptivity must embrace communication between maternal and embryonic tissues. At receptivity, the endometrium has reached a point at which negotiation can begin that may or may not lead to successful i...